Co-existing sarcoidosis, systemic lupus erythematosus and the antiphospholipid antibody syndrome
Identifieur interne : 001887 ( Main/Exploration ); précédent : 001886; suivant : 001888Co-existing sarcoidosis, systemic lupus erythematosus and the antiphospholipid antibody syndrome
Auteurs : Dr Wesemann [États-Unis] ; Kh Costenbader [États-Unis] ; Js Coblyn [États-Unis]Source :
- Lupus [ 0961-2033 ] ; 2009-03.
English descriptors
- Teeft :
- Anticardiolipin, Anticardiolipin antibodies, Antiphospholipid, Antiphospholipid antibodies, Antiphospholipid antibody syndrome, Antiphospholipid syndrome, Autoimmune, Autoimmune disease, Chest pain, Chest radiograph, Erythematosus, Granuloma, Lupus, Lupus sarcoidosis, Lymph nodes, Node, Noncaseating granulomas, Prognostic factor, Pulmonary sarcoidosis, Radiograph, Rash, Rheum, Rheumatoid arthritis, Rheumatol, Sarcoidosis, Semin arthritis rheum, Syndrome, Systemic, Systemic lupus erythematosus, Wesemann.
Abstract
Sarcoidosis, systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome (APS) are chronic conditions of immune dysregulation whose aetiologies remain mysterious. Expression of sarcoidosis and SLE within individuals has been reported in a handful of cases in the last 60 years. In this study, we report two cases of sarcoidosis and SLE occurring together, and each case demonstrated complications associated with the presence of anticardiolipin antibodies. Clinical, serological and pathological findings confirmed the diagnoses in each case and both patients improved with therapy. The association of sarcoidosis, SLE and APS is unique and may present difficult therapeutic options, as well as to shed light on their immunopathogenesis.
Url:
DOI: 10.1177/0961203308100483
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Sarcoidosis, systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome (APS) are chronic conditions of immune dysregulation whose aetiologies remain mysterious. Expression of sarcoidosis and SLE within individuals has been reported in a handful of cases in the last 60 years. In this study, we report two cases of sarcoidosis and SLE occurring together, and each case demonstrated complications associated with the presence of anticardiolipin antibodies. Clinical, serological and pathological findings confirmed the diagnoses in each case and both patients improved with therapy. The association of sarcoidosis, SLE and APS is unique and may present difficult therapeutic options, as well as to shed light on their immunopathogenesis.</div>
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